Post translation modification
Dear colleges,
i found a new single base mutation in coding sequence of a certain protein likely underlaying a herditary disease. Based on bioinformatic research in the international data base with Husar-CGC, this single base mutation produces a new recognation consensus sequence for myristylation. Now my question:
what´s the indication of the confidence in the software prediction of a new myristylation site ? How reliable is the prediction and what functional assay would be definitive proof that it is a real site? thank to you all in advance
Farhad
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